Search on: NUCLEAR RECEPTOR CO-REPRESSOR 2 
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Descriptor English:   Nuclear Receptor Co-Repressor 2 
Descriptor Spanish:   Co-Represor 2 de Receptor Nuclear 
Descriptor Portuguese:   Correpressor 2 de Receptor Nuclear 
Synonyms English:   Co-repressor, SMRT
Co-repressor, TRAC
Nuclear Receptor Co Repressor 2
Receptor-associating Factor, T3
SMRT Co repressor
SMRT Co-repressor
Silencing Mediator of Retinoic Acid and Thyroid Hormone Receptor
T3 Receptor associating Factor
T3 Receptor-associating Factor
TRAC Co repressor
TRAC Co-repressor  
Tree Number:   D12.776.930.780.625.400
Definition English:   A nuclear co-repressor protein that shows specificity for RETINOIC ACID RECEPTORS and THYROID HORMONE RECEPTORS. The dissociation of this co-repressor from nuclear receptors is generally ligand-dependent, but can also occur by way of its phosphorylation by members of the MAP KINASE SIGNALING SYSTEM. The protein contains two nuclear receptor interaction domains and four repressor domains and is closely-related in structure to NUCLEAR RECEPTOR CO-REPRESSOR 1. 
History Note English:   2010(1995) 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification DF deficiency
DE drug effects EC economics
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PH physiology
PO poisoning RE radiation effects
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UL ultrastructure UR urine
Record Number:   53661 
Unique Identifier:   D056985 

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